11/14/2023 0 Comments Nba live stream reddit![]() This page brings you NFL live streams, NBA live stream. Your home for Crackstreams of NFL Streams, NBA Streams, Boxing Streams Stream football, basketball games live on your PC, Mobile, Mac or tablet. WWE SummerSlam 2021 WWE Streams 08:00 pm ET WWE Streams for Wednesday, 30 August 2023 AWAY TEAM MMA Streams / UFC Streams for Wednesday, 30 August 2023 AWAY TEAM MotoGP Grand Prix of America GP BT Sport 2 04:20 am ETĬFB Streams / NCAAF Streams for Wednesday, 30 August 2023 AWAY TEAMīoxing Streams for Wednesday, 30 August 2023 Boxing Streams Live on ESPN+, FOX, DAZN Fight AWAY TEAMĮSPN Usyk 17 Boxing U.S. ![]() MotoGP America GP Free Practice Nr 1 Live Stream Moto3 Grand Prix of America GP BT Sport 2 03:25 am ET Moto3 America GP Free Practice Nr 1 Live Stream NFL Streams for Wednesday, 30 August 2023 AWAY TEAM NHL Streams for Wednesday, 30 August 2023 AWAY TEAM MLB Streams for Wednesday, 30 August 2023 AWAY TEAM NCAAM Streams / NCAA Men's Basketball for Wednesday, 30 August 2023 AWAY TEAM Golf Streams Online All Golf Games Everyday 8:00 am ET Nationally televised games will be linked on the middle of the table! AWAY TEAM We will offer both Away/Home games of crackstream, as well as nationally televised games! Some of the games will also feature NBA League Pass.Ĭlick on the logo of the team you wish to watch. We proudly announcing Due to the ban and down of, #crackstreams moved to buffstream.io NBA Streams for Wednesday, 30 August 2023 We have provided our site as an alternative to reddit ever since the subreddit /r/nbastreams was banned. The NBA has been experimenting with streaming the games on various platforms and it is showing promising results.Use "ctrl+d" to bookmark "buffstream.io" NBA Stream and NFL Stream Schedule Buffstream NBAStreams, NFLStreams and Crackstreams NBA streams are a great way to watch games. Fans can now watch their favorite teams on any device, regardless of location. Nowadays, NBA live streams are an important part of the fan experience. Sportsurge is the only live game streaming service that broadcasts all major sports in HD quality, with no ads. ![]() You can watch any game from any league, whether its NBA or MLB or NHL or NFL, with just one click of the mouse. Sportsurge is an app that lets you view sports games in real time, with no ads at all. So no matter what sport you love, we’ve got it covered for you! We'll cover every major sport, with the most popular games listed first. With its broadcast quality, it's like you're watching the game at home on TV - but you're not. The site provides an incredible viewing experience of the game. Sportsurge is an online platform for watching live games on any device. Watch All Your Favorite Sports With Sportsurge Sportsurge is a live streaming platform that allow you to watch NBA games on your phone. These features make it easy to find your perfect viewing experience for every NBA match. You can also choose from different commentators and styles of commentary. If you are looking for a more personalized experience, you can set up alerts for upcoming games and get notified when they are broadcasted. ![]() This gives you the opportunity to enjoy a match in HD, if your internet connection is strong enough, or watch it in a lower quality stream if your connection speeds are slow. Each match is available in multiple viewing streams. Sportsurge is an aggregator that allows NBA fans to watch all the NBA games in one place. Reddit NBA Streams Watch NBA on Sportsurge Streams ![]()
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11/14/2023 0 Comments Arabian jasmine![]() ![]() Whether you think your plants are getting too much water, cut back on how often you water them, and take the following measures to see if they might be nutritionally deficient: Overwatering or a lack of nutrients are the 2 main causes of this issue. Yellowing leaves are arguably the most prevalent issue in the gardening world. Why are my Arabian jasmine leaves turning yellow? This type of disease is one of the most frustrating for Arabian jasmine owners, we give you all the leads to spot and save your plants that present symptoms such as leaves that suddenly change color, or wilt/droop. Why does my Arabian jasmine have leaf spots? We urge you to cut off the infected roots and leaves, remove the affected sections of the plant, and then repot your plant in a fresh container with sterile potting soil. The majority of the time, it is caused by the Jasminum sambac being overwatered. When you understand the root of the issue, the solution makes perfect sense. ![]() You risk your plant dying if you ignore these warning indications. If you notice any brown (or gray) spots, this fungus is probably to cause. Gray mold spots are a specific fungus that regularly harms flowers and spreads swiftly. Why does my Arabian jasmine have gray mold spots? In order to keep your plant alive, we strongly suggest that you follow our advice if the signs start to show: blackened and mushy roots. Root rot on your Arabian jasmine (Jasminum sambac) can be dangerous if left untreated. Why does my Jasminum sambac roots have rot? These beautiful-smelling blooms appear all summer long and may bloom year-round in warm climates. The dark green leaves contrast nicely with the white flowers that fade to pink as they age. Jasmine tea and leis are made from Arabian jasmine, which is famous for its fragrant flowers. NOTE: Arabian jasmine may be referred to as Jasminum sambac in this article, in fact, those are the same plants, Jasminum sambac is the botanical name for Arabian jasmine. ![]() 11/14/2023 0 Comments Mozilla thunderbird portable mac![]() ![]() Since I have all my stored emails again, it is not such a keen loss. BUT, making sure the Install section of Profiles.ini had the correct profile name, I got my emails back- just not the Address Book which I will have to recreate from scratch. The critical part of the profiles.ini file (after naming Profile1 and Profile0, etc.) appears to be this section ref-ing the install.ini,ĭefault=Profiles/amon.b9.default where amon.b9.default is the actual, original profile with all your info.ĭiscovered this after much trial and error, since I really don't know this code. (Make notes of every you change in a text file!!! you will not remember if you get interrupted in this exercise.) I was under the mistaken impression that one of the more recently-created profiles was the desired one, and re-wrote the profile.ini file several times over trying to bring up my accounts & emails. TB created several new ones over the course of a transfer from an older computer to new OS upgrades. One must first make sure which profile is actually filled with your emails.Ĭan't stress this enough. This free email client enables Mac users to bring their email, contacts, address book and personalized messages with them while on the go. copy the new profile name, change that directory to "yyy", and rename your "xxx" folder with the copied nameĭavid, I used your technique -without success to recover my emails -UNTIL i realized that the profile.ini was critical. Portable Thunderbird for OS X is based purely on the Mozilla Thunderbird email client but has been made portable for Mac OS X users. in "Profiles", you should now see a new profile (that ends in default-release) and your old "xxx" folder the Finder window for "Library/Thunderbird" should now have a Profile.ini file deleted the newly created other profile renamed my old profile "fault-release" to "xxx" So here is what I did - INSURE THUNDERBIRD IS SHUT DOWN! There is a "Profile.ini" file (profile init) in this folder, it probably has the breadcrumbs for TB to determine what profile to use, but no matter how I fussed with it I could never get my old profile to work. The TB installer knew you had an old profile, but ignored it, and created this new one. All the action happens in "Library/Thunderbird"Īfter the new install, when you open the "Profiles" folder, you will probably see two profiles, your old one that should have tons of stuff in it, and a new one that ends with a "-1". Firefox Thunderbird Chromium All Programs Enterprise Deployment. ![]() There is a way to re-attach your old profile and I will detail that here.įirst, you will need to expose or open your 'Library' folder in Finder - you can also "Go" to that folder (google around if needed). This causes your existing "profile" to be forgotten, and TB installs a new one. Download Portable Thunderbird for Mac - Portable Thunderbird is the popular Mozilla Thunderbird email client packaged so you can carry around with you. I got the message that TB was corrupted, and re-installed as I read somewhere else. ![]() 11/13/2023 0 Comments Pierre robin sequence jacksonville fl![]() She was referred to our pediatric intensive care unit (PICU) on her second day of life for management of micrognathia and subsequent respiratory distress. A few minutes after delivery the baby girl went into acute respiratory distress and required urgent intubation, which proved difficult owing to her micrognathia and cleft palate. On physical examination, there were facial anomalies including micrognathia, retrodisplacement of the tongue causing airway obstruction, and cleft palate, which were consistent with a diagnosis of PRS mild ptosis and low set ears were also noted. Her birth weight was 3260 g, Apgar scores were 8/4/10 at 1, 5 and 10 min. The baby girl was born in a community hospital by cesarean section at 41 weeks gestation because of fetal decelerations. ![]() Information provided by the father suggested that cleft palate and mild to moderate micrognathia with no breathing problem were also a dominant trait in the family. The proband was an infant girl, the first child of two non-consanguineous parents with several members on the paternal side of the family diagnosed with lower-limb lymphedema and blepharitis. ![]() Our report thus emphasizes the association between LDS and PRS and advises distraction osteogenesis to resolve breathing problems in LDS patients who present with PRS related severe airway obstruction. Here we describe two Italian sisters with LDS confirmed by a FOXC2 mutation who presented with the classic triad described by Pierre Robin, i.e., micrognathia, glossoptosis and airway obstruction, associated with cleft palate, in whom the respiratory obstruction was severe to the point to require surgical treatment. Again, the diagnosis of PRS neglected to include airway or feeding problems. described a boy with LDS confirmed by a FOXC2 mutation who presented with ankyloglossia, glossoptosis, micrognathia, and cleft palate. identified inactivating mutations in the FOXC2 gene in two unrelated families with LDS, making molecular diagnosis possible. described cleft palate in three boys from different families, one case associated with PRS but, again, made no mention about possible breathing problems. In a large group of 18 families with LDS, Brice et al. For example, Temple et al., described the case of an infant with LDS presenting with cleft palate and micrognathia but no breathing problems. However, the lack of airway obstruction in most patients with LDS, micrognathia, and cleft palate, raises the question of whether the clinical manifestations in these patients are enough to fulfill the diagnosis of PRS. Micrognathia and cleft palate have been reported in 4 % of patients with LDS suggesting that PRS may be an associated feature of LDS. More than 40 syndromes with PRS have been described the most common of which involve connective disorders. PRS with or without cleft palate may be present as an isolated entity, as a component of a known syndrome, or associated with other malformations that have not been characterized as a known syndrome. In a later manuscript Robin mentioned that patients with PRS could have an associated cleft palate. ![]() Pierre Robin sequence was described in 1923 by the French stomatologist, Pierre Robin, as a range of findings consisting of breathing problems in patients with glossoptosis and associated microagnathia. Following the first description made by Campbell in 1945, several additional manifestations with variable expression have been reported such as ptosis, varicose veins, congenital heart disease, spinal extradural cysts, and cleft palate with or without Pierre Robin sequence (PRS). Lymphedema–distichiasis syndrome (LDS) is a rare, highly penetrant autosomal dominant disorder characterized by late onset lower-limb lymphedema, and distichiasis, a congenital abnormality in which extra-eyelashes grow from the Meibomian glands and protrude into the cornea causing irritation. ![]() 11/13/2023 0 Comments Bvckup core server![]() ![]() I love to support well crafted native software so don't take this as a negative question. I'm trying to wrap my head around the use case here. If anyone has any questions, I'd be happy to answer them if I can as well. I'm also the original author of Hamachi VPN, there's a chance you might've heard of it.Īny thoughts or comments on the program itself, would appreciate to hear them. which is one of the reasons I still like things to be as small and as fast as possible. I've been a programmer for my entire life, mostly on the sysdev side of things - firewalls, network stacks, VPNs, etc. If you are thinking of trying the Windows ISV path, I'd aim there.īy the way of introduction - I'm in my mid 40s. They acknowledge and compliment it, and they are actively looking for it. The biggest takeaway has been that there is LOTS of people, on Windows, that recognize software quality as a feature. The demand for well-written Windows software is still there. Secondly, I wanted to add an anecdotal data point that the desktop software development is still very much an option despite of all the nasty rumors. The blog captures some of that in a form of development screenshots, sketches and what not. Said No to more feature requests than I can remember. Half of the development time was sunk into the UI/UX design, so there's that too.Įxisting version is a result of 5 years of a _very_ careful evolution, focusing more on perfecting existing features rather than adding new ones. It is light, very small and it is really quite fast. It can be used for both mirroring and archiving backups, among other things. If you are familiar with "robocopy /mir" - same idea, but on steroids. Its primary purpose is to do very fast file replication. I obviously want to show my baby to those who haven't seen it. I thought I'd do a Show HN for two reasons.ġ. This is a long-running project that started as the proverbial need to scratch my own itch and then somehow evolved into a full-time job of the past 6 years. ![]() 11/13/2023 0 Comments Update homebrew![]() brew -prefix -installed is a new flag to brew -prefix that will fail if the requested formula is not installed.Fixed a bug where brew update could be run every time.brew info -cask -json=v2 includes whether a cask is outdated and the currently installed versions.brew casks is a new command implemented in Bash to speedily output all casks available to install (like brew formulae).Homebrew/homebrew-cask) will ensure it’s no longer automatically retapped brew untap of an official tap you don’t use (e.g.brew audit reads more formula data from taps.Command usage text is automatically generated (so will be kept-up-to-date).Other changes since 2.7.0 I’d like to highlight are the following: brew completions is a new command to opt-in to completions provided by third-party taps.brew update better handles upstream branch renames (e.g.This will ensure they are kept up-to-date. Bash, fish and zsh completions are generated automatically from the CLI::Parser DSL.Various methods have been deprecated, disabled and removed.This does not work (yet) on Apple Silicon or using Homebrew’s portable Ruby. The new HOMEBREW_BOOTSNAP environment variable allows the use of the Bootsnap gem to speed up repeated brew calls.This will allow more bottles to be relocatable. brew style -fix will autocorrect formulae to this new format. brew bottle and bottle do blocks use a new syntax format (one :cellar per platform).Rosetta 2 on Apple Silicon still provides support for Intel x86_64 in /usr/local. Homebrew doesn’t (yet) provide bottles for all packages on Apple Silicon that we do on Intel x86_64 but we welcome your help in doing so. ![]() formula pages indicate for which platforms bottles (binary packages) are provided and therefore whether they are supported by Homebrew.
11/13/2023 0 Comments Luxury carbon fiber wallet![]() ![]() It features real carbon fiber in 3K twill matte finish. The elastic band features a Jeep Grill to really make this wallet unique. The Jeep letters and socket head screws are raised to give a unique industrial look and feel to the wallet. His cards and cash are held securely yet are easily accessible. This slim, Carbon Fiber Jeep Wallet is lightweight, durable, and is easy to carry in his front pocket. Carbon Fiber makes this wallet extremely durable but at the same time very flexible. This Leather Thin Minimalist Front Pocket Wallet can hold up to 15 notes folded 4 ways / 30 notes folded in half or 5 cards on each side. It is slightly bigger than a credit card and has the same thickness as one. ![]() Leather Thin Minimalist Front Pocket Wallet He will certainly treasure this gift for a long time. It's one gift that is both functional and stylish. The Carbon Fiber Wallet For Men is a slim, light and flexible wallet that can hold up to 12 cards. It is designed to replace that brick in his pocket. It's easy to string together around his stack of cards so he sets how tight he wants it to be, enough to squeeze his cards/cash but loose enough to that he can add more if need be. Let him replace that bulky leather wallet and protect his identity with this 3k twill genuine Carbon Fiber Tactical Minimalist Wallet fastened together with military grade 1/16" shock cord. It is light weight, and features RFID blocking, sturdy and sleek. Hood Oregon Carbon Fiber Wallet has dual 2mm carbon fiber plate with chamfered edges that is easy on the hands and on the eyes. It will definitely provide him with good organization and security. It has anti-theft features, is multifunctional and has 14 internal card slots, 2 large cash pockets and 1 ID Window. This carbon fiber case is treated with scratch resistant technology to make the it more durable and stylish. The Minimalist Carbon Fiber Clutch Walletis made of high-quality Carbon Fiber Material on the outside and of high-grade cowhide on the inside. It is considered a minimalist wallet so fewer cards are better unless he likes the bulk.ĩ. The elastic band expands to accommodate 1-12 cards. It can hold up to 12 cards and has a money strap for your cash. This drift wallet is constructed of two black aluminum plates, which blocks RFID theft. This Carbon Fiber Wallet is the slimmest wallet he will ever own. Have him upgrade with this versatile hybrid slim wallet for men. Time for him to ditch that bulky, back breaking wallet. It features nylon lining and a snap closure. The Carbon Fiber Money Clip is made from crazy horse leather, a top-quality leather, wax treated, water-resistant & extremely durable. This heavy-duty woven nylon offers enhanced tear & abrasion resistance. It's definitely a great gift for any husband or boyfriend. This engraved wallet also comes with RFID (wireless theft) protection so he can know his ID is safe from all bad guys. It's slim enough to keep his pockets looking good but large enough for 12 cards and his cash this is best of all worlds. Bottle Opener Carbon Fiber Minimalist Wallet This RFID wallet not only offers security but is also very functional. It features 6 card slots for him to place his most frequently used cards. It has a size that is extremely convenient to be carried around in his front or back pocket. It features an RFID blocking up to 13.56 MHz frequency with PU Leather lining. But that is certainly not true with this Minimalist Carbon Fiber Wallet. The carbon fiber outer case is treated with anti-scratch technology to give a longer-lasting, better-looking wallet with a much better feel to it. This one-of-a-kind carbon fiber slim wallet money clip can hold up to 12 credit cards and 9 bills at once. This Minimalist Aluminum Wallet is made of top-quality material inside and out. It's simple, convenient, and dependable. It's one gift that he will treasure for a long time. It features a q uick card access of up to 6 cards plus cash storage. It is made with h igh quality material and 100% real carbon fiber. This Carbon Fiber Color Limited Edition Wallet is designed with aluminum color washer, O-ring, screw and back carbon fiber elastic for the cash. Carbon Fiber Color Limited Edition Wallet Here are 15 of the best carbon fiber wallets you can choose from: 15. What’s more, because of its unique properties, it has a a unique and distinct appearance that he will surely love. It is comfortable when in his pocket while also emphasizing modern yet masculine style. It is 10 times stronger and 5 times lighter than steel. These wallets ate made with the best in class CX6 carbon fiber which has the highest tensile strength amongst any fiber on the market. The closest that you can probably give is a carbon fiber wallet. Looking for a gift that fits that description can be quite challenging. ![]() 11/13/2023 0 Comments Laser tag games for home![]() ![]() It encourages leadership, stress relief, and team bonding while providing a great workout.If you're looking for a way to bring the excitement of laser tag into your home, you may be wondering what the best laser tag game for home use is. Laser tag is a fun, cool, and immersive experience that is perfect for team building. At the conclusion of the program, your coworkers should be better acquainted with one another and communicate more effectively. Great Team Bonding ActivityĪ thrilling laser tag game builds teamwork and communication, promotes team bonding, and all of these are essential in the workplace. Lasertag is one of the best methods to relax after a long day at work because it combines elements of fun, a sweaty-good workout, and the ability to shoot someone without facing legal ramifications. It’s a win-win situation for businesses seeking to identify leaders from followers: laser tag team building activities. Natural charisma and leadership ability may shine through in laser tag, which requires planning, precision, and cooperation. As a result, it’s difficult to determine who among the staff is most suited to lead. It’s also about how they act as individuals, and how they react if put in a scenario. It’s not just about a person’s qualifications that determine whether or not they’re a leader. In comparison to other team building activities that require just as much physical activity, this disadvantage appears to be quite minor. The main risk associated with laser tag is getting hurt while running about. Laser Tag indoor is quite safe when it comes to firearms. It’s an unusual and original take on the usual tag game, making for a fresh and unique experience that everyone should play at least once. Lightweight laser guns are used in laser tag games, which entail chasing around with each other while wearing light clothes and shooting each other. Laser tag, on the other hand, offers a unique experience. While many people have played tag as children, others have enjoyed laser guns. There’s nothing more immersive than attempting to hide in plain sight and fire upon your foes while playing with your inner kid. ![]() Laser tag is one of the most dramatic examples where a team building activity goes from being an immersive and enjoyable experience to being solely an entertaining experience. ![]() Fun, Cool and ImmersiveĪlthough team building exercises might be either immersive or enjoyable, they are almost never both. ![]() Our laser tag experience offers a thrilling, intense, and realistic simulated combat experience with 5 different gameplay modes to choose from! Players will have an amusing time and a memorable encounter with gameplay modes including free for all, Capture the Flag, Elimination, Medic, and Battlefield. They will fire at the infrared-sensitive targets worn by the participants. It came from a gaming and arcade variation that some of you may be familiar with! The game includes Laser Tag indoor and outdoor sessions in which players use infrared ray guns. The FunEmpire Laser Tag game has emerged to become one of the most popular games in recent years. Reasons To Play Laser Tag What is Laser Tag? ![]() 11/13/2023 0 Comments Scenery drawing easy and beautiful![]() The textural look often comes from effective shading that is easier (relatively) using a pencil.Artist's Guide to World Wildlife continues a rich tradition of animals in art and gives readers the basic information on art materials, fundamental mechanics of drawing, species and locale-specific details, and process instructions so that even beginners will feel confident and succcessful as they learn to produce highly detailed, lifelike drawings of these beautiful animals.385 Line Drawing Animals Stock Photos, Images & Pictures Most relevant Best selling Latest uploads Within Results People Pricing License Media Properties More Safe Search line line drawing safari animals animal line drawing Browse 385 professional line drawing animals stock photos, images & pictures available royalty-free. The textural look often comes …There are pencils that come in various levels of thickness that can be used for drawing thinner lines, for filling in, for shading and other things to create a realistic drawing. There are pencils that come in various levels of thickness that can be used for drawing thinner lines, for filling in, for shading and other things to create a realistic drawing. See more ideas about drawings, animal drawings, animal art. Brushes for Petals- 37 Brushes.Wildlife sketches and drawings. 59 29 USD *Commercial license: +25 USD (select at checkout). Wildlife Art Made Easy - Draw Wild Animal Outlines in Procreate With Just One Tap! 30 Unique Critters Ready to Be Brought to Life With One Click. Deserts, plains, grasslands, woodlands, forests, and other areas, including the most developed urban areas. Wildlife was also synonymous to game: those birds and mammals that were hunted for sport.Wildlife can be found in all ecosystems. ![]() eps ) formatWildlife refers to undomesticated animal species, but has come to include all organisms that grow or live wild in an area without being introduced by humans. ai ) format, Encapsulated PostScript eps (. cdr format free and easy download unlimit id:6833530 Wildlife drawing frogs pond lotus icons colored cartoon - Author: - Adobe Illustrator ai (. See more ideas about flower drawing, wildflower drawing, flower doodles.Wildlife drawing frogs pond lotus icons colored cartoon Vectors graphic art designs in editable. Explore Marion Deering's board "Wildflower drawing" on Pinterest. A convenient floorplan, walkout basement, 3 car garage this home has much to offer any family that loves. This available opportunity consists of an incredible 2700 sq ft bungalow home built in 2008 with sweeping vista views. Residents who call River Road home are drawn to the convenient location, rural lifestyle on offer and all the benefits these bring. ![]() ![]() You can turn your walls into a forest glade teeming with woodland wildlife, a savannah featuring the amazing animals of Africa, or a wetland area swarming with thousands of migratory birds.Presenting an opportunity like no other. …Wildlife Drawings Bring the magic of nature indoors with our drawings of wildlife in your home or office. You can turn your walls into a forest glade teeming with woodland wildlife, a savannah featuring the amazing animals of Africa, or a wetland area swarming with thousands of migratory birds. ![]() Bring the magic of nature indoors with our drawings of wildlife in your home or office. The Definitive Guide to Planting Food Plots - Media Mail | The Deer DoctorChoose your favorite wildlife drawings from 23,170 available designs. ![]() 11/13/2023 0 Comments Tinc n juice![]() Received: JAccepted: OctoPublished: November 16, 2015Ĭopyright: © 2015 Novak et al. PLoS ONE 10(11):Įditor: Barbara Bardoni, CNRS UMR7275, FRANCE Taken together, our findings support the hypothesis that dFmr1 protein is essential for proper cardiac function and establish the fly as a new model for studying the role(s) of FraX proteins in the heart.Ĭitation: Novak SM, Joardar A, Gregorio CC, Zarnescu DC (2015) Regulation of Heart Rate in Drosophila via Fragile X Mental Retardation Protein. Interestingly, these functional defects are not accompanied by any obvious structural abnormalities, suggesting that dFmr1 may regulate a different repertoire of targets in Drosophila than in vertebrates. Functional analyses in the context of cardiac-specific dFmr1 knockdown by RNAi demonstrate that dFmr1 is required cell autonomously in cardiac cells for regulating heart rate. Using classical loss of function alleles as well as muscle specific RNAi knockdown, we show that Drosophila FMRP, dFmr1, is required for proper heart rate during development. To decipher the direct role of FraX proteins in the heart in vivo, we turned to Drosophila, which harbors a sole, functionally conserved and ubiquitously expressed FraX protein, dFmr1. FraX proteins are established regulators of translation and are known to regulate specific targets in different tissues. More recently, alterations in the levels of Fragile X Related 1 protein, FXR1, the predominant FraX member expressed in vertebrate striated muscle, have been linked to structural and functional defects in mice and zebrafish models. ![]() ![]() The Fragile X (FraX) family of RNA binding proteins is most commonly studied in the context of neurological disorders, as mutations in Fragile X Mental Retardation 1 (FMR1) are the leading cause of inherited mental retardation. RNA binding proteins play a pivotal role in post-transcriptional gene expression regulation, however little is understood about their role in cardiac function. ![]() |
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